Merkel Cells Definition

Although their origin is unclear they are thought to arise from epidermal ectoderm rather than neural crest. Medical Definition of Merkel cell.

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A cell present in a neoplasm and differentiated from normal tissue cells because of its degree of anaplasia irregularity of shape nuclear size changes in the structure of the nucleus and cytoplasm increased number of mitoses and ability to metastasize.

Merkel cells definition. Merkel cells are epithelial neuroendocrine cells. A cell that occurs in the basal part of the epidermis is characterized by dense granules in its cytoplasm is closely associated with the unmyelinated tip of a nerve fiber and probably functions in tactile sensory perception. Merkel cells are rare and are found in the basal layer of the epidermis and around the bulge region of hair.

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